Hepatic macrophage targeted siRNA lipid nanoparticles treat non-alcoholic steatohepatitis
Jinge Zhou, Lei Sun, Li Liu, Yujie Jia, Yuqiao Han, Jiaqi Shao, Jing Wang, Yiting Wang, Lei Yu, Zhiqiang Yan
Topics & Concepts
SteatohepatitisMannose receptorFatty liverSteatosisCirrhosisHMGB1MacrophageInflammationDocosahexaenoic acidBiologyMedicineCancer researchPharmacologyImmunologyBiochemistryFatty acidInternal medicinePolyunsaturated fatty acidIn vitroDiseaseLiver Disease Diagnosis and TreatmentLiver physiology and pathologyRNA Interference and Gene Delivery