In silico prediction of post-translational modifications in therapeutic antibodies
Shabdita Vatsa
Abstract
prediction of novel modifications in antibodies, and predict the impact of modifications on physical stability and antigen-binding.
Topics & Concepts
DeamidationIn silicoChemistryMonoclonal antibodyComputational biologyCombinatorial chemistryAntibodyBiochemistryEnzymeBiologyImmunologyGeneMonoclonal and Polyclonal Antibodies ResearchProtein purification and stabilityGlycosylation and Glycoproteins Research