Metatranscriptomic Analysis Reveals SARS-CoV-2 Mutations in Wastewater of the Frankfurt Metropolitan Area in Southern Germany
Shelesh Agrawal, Laura Orschler, Susanne Lackner
Abstract
We report a sequencing analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in wastewater samples collected in the Frankfurt metropolitan area of Germany. The majority of the detected mutations have been identified only in clinical genomes outside Frankfurt, indicating that the sequencing of SARS-CoV-2 RNA in wastewater can provide insights into emerging variants in a city.
Topics & Concepts
Metropolitan areaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)WastewaterCoronavirus disease 2019 (COVID-19)VirologyCoronavirus2019-20 coronavirus outbreakBiologyRNAMutationGeneticsGeographyGeneMedicineInternal medicineEnvironmental scienceEnvironmental engineeringArchaeologyOutbreakInfectious disease (medical specialty)DiseaseSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 and COVID-19 Research