Analysis of the mechanism of action of quercetin in the treatment of hyperlipidemia based on metabolomics and intestinal flora
Tongtong Wang, Ling Liu, Jun Deng, Yu Jiang, Xiao Yan, Wen Liu
Abstract
was closely related to the change of differential metabolites. In summary, combined with metabolomics and gut microbiota studies, it is found that QUE can reduce lipid levels and improve liver function. The potential mechanism may be the regulation of metabolism and intestinal flora that play a role in reducing lipid levels, to achieve the purpose of treatment of HLP.
Topics & Concepts
MetabolomicsGut floraFirmicutesBacteroidesHyperlipidemiaBiologyBacteroidetesBacteroides fragilisLipid metabolismMicrobiologyBiochemistryPharmacologyBacteriaEndocrinologyAntibioticsBioinformaticsGeneticsGene16S ribosomal RNADiabetes mellitusMetabolomics and Mass Spectrometry StudiesGut microbiota and healthDiet and metabolism studies