Design and synthesis of novel mitochondria-targeted CDDO derivatives as potential anti-cancer agents
Wei Ju, Na Li, Junjie Wang, Nairong Yu, Zhichao Lei, Lulu Zhang, Jianbo Sun, Li Chen
Topics & Concepts
ChemistryMitochondrionOleanolic acidApoptosisMembrane potentialCancer cellSelectivityInner mitochondrial membraneProgrammed cell deathCellBiochemistryCell biologyCancer researchCancerBiologyPathologyMedicineGeneticsCatalysisAlternative medicineGenomics, phytochemicals, and oxidative stressATP Synthase and ATPases ResearchCancer therapeutics and mechanisms