Contact lens-based lysozyme detection in tear using a mobile sensor
Zachary S. Ballard, Sarah Bazargan, Diane Jung, Shyama Sathianathan, Ashley Clemens, Daniel Shir, Saba Al-Hashimi, Aydogan Özcan
Abstract
). Taken together, this study demonstrates tear-fluid analysis with simple and non-invasive sampling steps along with a rapid, easy-to-use, and cost-effective measurement system, ultimately indicating physiological differences in human participants. We believe this method could be used in future tear-fluid studies, even supporting multiplexed detection of a panel of tear biomarkers toward improved diagnostics and prognostics as well as personalized mobile-health applications.
Topics & Concepts
Contact lensLens (geology)BiomarkerLysozymeComputer scienceMobile deviceChemistryOpticsOphthalmologyMedicineBiochemistryPhysicsOperating systemOcular Surface and Contact LensBiosensors and Analytical DetectionGaze Tracking and Assistive Technology