Development of a DNA Adductome Mass Spectral Database
Jingshu Guo, Robert J. Turesky, Anamary Tarifa, Anthony P. DeCaprio, Marcus S. Cooke, Scott J. Walmsley, Peter W. Villalta
Abstract
Mass spectrometry-based DNA adductomics is an emerging approach for the human biomonitoring of hazardous chemicals. A mass spectral database of DNA adducts will be created for the scientific community to investigate the associations between chemical exposures, DNA damage, and disease risk.
Topics & Concepts
BiomonitoringDNAMass spectrometryHazardous wasteEnvironmental chemistryChemistryDatabaseComputational biologyComputer scienceBiologyChromatographyBiochemistryEcologyCarcinogens and Genotoxicity AssessmentToxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicals