Novel PDE5 inhibitors derived from rutaecarpine for the treatment of Alzheimer’s disease
Xianfeng Huang, Yanhua Dong, Jinhui Wang, Hengming Ke, Guoqiang Song, Defeng Xu
Topics & Concepts
RutaecarpineChemistryPharmacologyIn vivoIC50StereochemistryIn vitroBiochemistryMedicineChromatographyBiologyBiotechnologyPhosphodiesterase function and regulationChemical synthesis and alkaloidsCholinesterase and Neurodegenerative Diseases