The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation
Alessandra Bearz, Elisa De Carlo, Alessandro Del Conte, Michele Spina, Valentina Da Ros, Elisa Bertoli, Alberto Revelant, Brigida Stanzione, Umberto Tirelli
Abstract
The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the most important paradigmatic shifts in the prognosis and treatment for this subgroup population occurred among lung cancer.
Topics & Concepts
Lung cancerChromosomal translocationOncologyMedicineInternal medicinePopulationCancerLungCancer researchBiologyGeneGeneticsEnvironmental healthLung Cancer Treatments and MutationsLung Cancer Research StudiesNeuroendocrine Tumor Research Advances