Parameter Reliability and Understanding Enzyme Function
Andrew G. McDonald, Keith F. Tipton
Abstract
Knowledge of the Michaelis-Menten parameters and their meaning in different circumstances is an essential prerequisite to understanding enzyme function and behaviour. The published literature contains an abundance of values reported for many enzymes. The problem concerns assessing the appropriateness and validity of such material for the purpose to which it is to be applied. This review considers the evaluation of such data with particular emphasis on the assessment of its fitness for purpose.
Topics & Concepts
Reliability (semiconductor)Function (biology)Meaning (existential)Management scienceComputer scienceBiochemical engineeringPsychologyBiologyEngineeringPhysicsThermodynamicsPsychotherapistEvolutionary biologyPower (physics)Enzyme Catalysis and ImmobilizationBiotin and Related StudiesMicrobial Metabolic Engineering and Bioproduction