Development of carbon nanotube-based polymer-modified electrochemical sensor for the voltammetric study of Curcumin
Pemmatte A. Pushpanjali, J. G. Manjunatha, Balliamada M. Amrutha, N. Hareesha
Abstract
The applicability of Curcumin (CRC) as a medicinal remedy for various health issues and as an anti-inflammatory agent, it is of great importance to develop an effortless, sensitive methodology for its determination. In the present research, CRC was determined electrochemically via voltammetric techniques using poly(L-arginine) modified carbon nanotube paste sensor (PArMCNTPS). Different parameters (pH, scan rate, number of polymerisation cycle) were optimised using cyclic voltammetry. CRC displayed well-defined oxidative and reductive peaks at 0.24 V and 0.16 V, respectively. The efficacy of the electrode towards the concurrent detection of CRC was examined in the presence of Riboflavin and Ascorbic acid. Detection of CRC by PArMCNTPS through differential pulse voltammetry technique was achieved from 2 × 10−7 M to 5 × 10−6 M and it presents adequately low detection (6.62 × 10−8 M) and quantification (2.20 × 10−7 M) limits. Furthermore the developed sensor was employed to determine CRC in turmeric powder to validate its analytical application.