Fatty Acid Synthesis in Glial Cells of the CNS
Aida V. Garcia Corrales, Mansour Haidar, Jeroen F. J. Bogie, Jerome J. A. Hendriks
Abstract
Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer's disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases.
Topics & Concepts
Central nervous systemMultiple sclerosisHomeostasisNeuroscienceInflammationDiseaseMicrogliaBiologyNervous systemBrain functionMedicineImmunologyCell biologyPathologyNeuroscience and Neuropharmacology ResearchCannabis and Cannabinoid ResearchCholesterol and Lipid Metabolism