Integration of rare expression outlier-associated variants improves polygenic risk prediction
Craig Smail, Nicole M. Ferraro, Qin Hui, Matthew G. Durrant, Matthew Aguirre, Yosuke Tanigawa, Marissa R. Keever-Keigher, Abhiram Rao, Johanne Marie Justesen, Xin Li, Michael J. Gloudemans, Themistocles L. Assimes, Charles Kooperberg, Alex P. Reiner, Jie Huang, Christopher J. O’Donnell, Yan V. Sun, Manuel A. Rivas, Stephen B. Montgomery
Topics & Concepts
Polygenic risk scoreComputational biologyOutlierExpression (computer science)Expression quantitative trait lociBiologyEvolutionary biologyGeneticsComputer scienceArtificial intelligenceGeneSingle-nucleotide polymorphismGenotypeProgramming languageGenetic Associations and EpidemiologyRNA modifications and cancerGenomics and Rare Diseases