Litcius/Paper detail

A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response

Advait Subramanian, Lan Wang, Tom Moss, Mark Voorhies, Smriti Sangwan, Erica Stevenson, Ernst H. Pulido, Samentha Kwok, Robert J. Chalkley, Kathy H. Li, Nevan J. Krogan, Danielle L. Swaney, Alma L. Burlingame, Stephen N. Floor, Anita Sil, Peter Walter, Shaeri Mukherjee

2023Nature Cell Biology35 citationsDOIOpen Access PDF

Topics & Concepts

Translation (biology)MimicryMolecular mimicryTransfer RNABiologyToxinCell biologyTransferasePeptidyl transferaseProtein biosynthesisMicrobiologyBiochemistryEnzymeRNAGeneticsAntigenMessenger RNARibosomeGeneEcologyLegionella and Acanthamoeba researchToxoplasma gondii Research StudiesRNA and protein synthesis mechanisms