A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
Advait Subramanian, Lan Wang, Tom Moss, Mark Voorhies, Smriti Sangwan, Erica Stevenson, Ernst H. Pulido, Samentha Kwok, Robert J. Chalkley, Kathy H. Li, Nevan J. Krogan, Danielle L. Swaney, Alma L. Burlingame, Stephen N. Floor, Anita Sil, Peter Walter, Shaeri Mukherjee
Topics & Concepts
Translation (biology)MimicryMolecular mimicryTransfer RNABiologyToxinCell biologyTransferasePeptidyl transferaseProtein biosynthesisMicrobiologyBiochemistryEnzymeRNAGeneticsAntigenMessenger RNARibosomeGeneEcologyLegionella and Acanthamoeba researchToxoplasma gondii Research StudiesRNA and protein synthesis mechanisms