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The structure and regulation of the E3 ubiquitin ligase HUWE1 and its biological functions in cancer

Xiaofeng Gong, Danyu Du, Yanran Deng, Yuqi Zhou, Li Sun, Shengtao Yuan

2020Investigational New Drugs101 citationsDOI

Topics & Concepts

Ubiquitin ligaseUbiquitinRegulatorDNA ligaseBiologyCell biologyComputational biologyUbiquitin-Protein LigasesCancer researchGeneGeneticsUbiquitin and proteasome pathwaysProtein Degradation and InhibitorsCancer-related Molecular Pathways
The structure and regulation of the E3 ubiquitin ligase HUWE1 and its biological functions in cancer | Litcius