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Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo

Jimmy K. Guo, Mario R. Blanco, Ward G. Walkup, Grant Bonesteele, Carl R. Urbinati, Abhik K. Banerjee, Amy Chow, Olivia Ettlin, Mackenzie Strehle, Parham Peyda, Enrique Amaya, Vickie Trinh, Mitchell Guttman

2024Molecular Cell88 citationsDOIOpen Access PDF

Topics & Concepts

BiologyPRC2ChromatinRNARNA-binding proteinNon-coding RNACell biologyLong non-coding RNAGeneticsComputational biologyGeneEZH2Cancer-related molecular mechanisms researchRNA modifications and cancerRNA Research and Splicing
Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo | Litcius