Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
Jimmy K. Guo, Mario R. Blanco, Ward G. Walkup, Grant Bonesteele, Carl R. Urbinati, Abhik K. Banerjee, Amy Chow, Olivia Ettlin, Mackenzie Strehle, Parham Peyda, Enrique Amaya, Vickie Trinh, Mitchell Guttman
Topics & Concepts
BiologyPRC2ChromatinRNARNA-binding proteinNon-coding RNACell biologyLong non-coding RNAGeneticsComputational biologyGeneEZH2Cancer-related molecular mechanisms researchRNA modifications and cancerRNA Research and Splicing