Cardiovascular Complications of Acetylcholinesterase Inhibitors in Patients with Alzheimer’s Disease: A Narrative Review
Sara Young, Enoch Chung, Michael A. Chen
Abstract
While acetylcholinesterase inhibitors are used to treat a wide range of patients with Alzheimer's disease, acetylcholinesterase inhibitor use has also been associated with a variety of cardiovascular complications, including bradycardia and syncope. Herein, we review the pathophysiology and clinical evidence for cardiovascular complications caused by acetylcholinesterase inhibitors in patients being treated for dementia and discuss options for their management.
Topics & Concepts
AcetylcholinesteraseMedicineDiseaseNarrative reviewDementiaAcetylcholinesterase inhibitorBradycardiaPathophysiologyIntensive care medicineBioinformaticsInternal medicineBlood pressureEnzymeBiologyBiochemistryHeart rateCholinesterase and Neurodegenerative DiseasesEpilepsy research and treatmentTreatment of Major Depression