In vitro screening of per- and polyfluorinated substances (PFAS) for interference with seven thyroid hormone system targets across nine assays
Sigmund J. Degitz, Jennifer H. Olker, Jeffery S. Denny, Philip P. Degoey, Phillip C. Hartig, Mary C. Cardon, Stephanie A. Eytcheson, Jonathan T. Haselman, Sally A. Mayasich, Michael W. Hornung
Topics & Concepts
Iodothyronine deiodinaseThyroid peroxidaseDeiodinaseThyroglobulinDIO2ThyroidChemistryPotencyIn vitroTransthyretinHormoneIn vivoBiochemistryInternal medicineEndocrinologyBiologyTriiodothyronineMedicineGeneticsPer- and polyfluoroalkyl substances researchChemical Analysis and Environmental ImpactEffects and risks of endocrine disrupting chemicals