Degradomics defines proteolysis information flow from human knee osteoarthritis cartilage to matched synovial fluid and the contributions of secreted proteases ADAMTS5, MMP13 and CMA1 to articular cartilage breakdown
Sumit Bhutada, Anna Hoyle, Nicolás S. Piuzzi, Suneel Apte
Topics & Concepts
ProteasesSynovial fluidCartilageOsteoarthritisProteolysisExtracellular matrixChemistryPathogenesisCell biologyPathologyMedicineAnatomyBiologyBiochemistryEnzymeAlternative medicineOsteoarthritis Treatment and MechanismsAsthma and respiratory diseasesRheumatoid Arthritis Research and Therapies