Review and Prospect of Pathological Features of Corona Virus Disease.

H J Wang, Songlin Du, Xia Yue, C X Chen

2020PubMed72 citationsDOI

Abstract

ABSTRACT: Since 2003, coronavirus has caused multiple major public health events that resulted in global epidemics, such as severe acute respiratory syndrome （SARS）, Middle East respiratory syndrome （MERS） and corona virus disease 2019 （COVID-19）. Especially since COVID-19 outbroke in Wuhan, Hubei, in December 2019, coronavirus has had a significant impact on people's health and lives. But so far, the pathological diagnosis of COVID-19 has been relatively deficient： it is still confined to the pathological findings of punctured organs, and the majority of medical workers have poor awareness of its pathological characteristics. The COVID-19, as same as SARS and MERS, is caused by coronaviruses and can cause viral pneumonia. They have certain similarities. This article comprehensively reviews the pathological features observed in the autopsies of the aforementioned three diseases, in order to provide reference to the analysis of pathological changes of COVID-19.

Topics & Concepts

PathologicalCoronavirus disease 2019 (COVID-19)Middle East respiratory syndrome coronavirusMiddle East respiratory syndromeCoronavirusPneumoniaDiseaseVirusMedicineVirus diseasesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Severe acute respiratory syndromeVirologyPathologyInfectious disease (medical specialty)Internal medicineCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19