Enhancing the ROS generation ability of a rhodamine-decorated iridium(<scp>iii</scp>) complex by ligand regulation for endoplasmic reticulum-targeted photodynamic therapy
Lihua Zhou, Fangfang Wei, Jingjing Xiang, Hongfeng Li, Chunbin Li, Pengfei Zhang, Chuangjun Liu, Ping Gong, Lintao Cai, Keith Man‐Chung Wong
Abstract
near infrared fluorescence (NIRF) imaging and tumour PDT were investigated and showed preferential accumulation at the tumour site and remarkable tumour growth suppression, respectively.
Topics & Concepts
Endoplasmic reticulumIridiumPhotodynamic therapyLigand (biochemistry)ChemistryRhodamineCell biologyReceptorBiochemistryBiologyFluorescenceCatalysisOrganic chemistryPhysicsQuantum mechanicsAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranosticsNanocluster Synthesis and Applications