Mussel Inspired Chemistry and Bacteria Derived Polymers for Oral Mucosal Adhesion and Drug Delivery
Nazanin Owji, Nandin Mandakhbayar, David A. Gregory, Elena Marcello, Hae-won Kim, Ipsita Roy, Jonathan C. Knowles
Abstract
biocompatibility was investigated in a rat model where the polydopamine coated PHA showed less inflammatory response over time compared to uncoated samples with sign of neovascularization. In conclusion, this simple mussel inspired polydopamine chemistry introduces a step change in bio-surface functionalization and holds great promise for the treatment of oral conditions.
Topics & Concepts
MusselCoatingAdhesionDrug deliveryChemistryPolymerBacteriaPolymer scienceDrugNanotechnologyChemical engineeringBiophysicsBiochemistryMaterials scienceOrganic chemistryBiologyEcologyPharmacologyEngineeringGeneticsPolymer Surface Interaction StudiesOral and gingival health researchElectrospun Nanofibers in Biomedical Applications