Chemopreventive effects of hesperidin against paclitaxel-induced hepatotoxicity and nephrotoxicity via amendment of Nrf2/HO-1 and caspase-3/Bax/Bcl-2 signaling pathways
Cihan Gür, Fatih Mehmet Kandemır, Cüneyt Çağlayan, Emine Satıcı
Topics & Concepts
PharmacologyHesperidinOxidative stressToxicityApoptosisNephrotoxicityGCLCChemistryCaspase 3Lipid peroxidationGlutathioneMedicineInternal medicineProgrammed cell deathBiochemistryEnzymePathologyAlternative medicineChemotherapy-induced organ toxicity mitigationDrug-Induced Hepatotoxicity and ProtectionNigella sativa pharmacological applications