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m6A-induced lncRNA MALAT1 aggravates renal fibrogenesis in obstructive nephropathy through the miR-145/FAK pathway

Peihua Liu, Bo Zhang, Zhi Chen, Yao He, Yongchao Du, Yuhang Liu, Xiang Chen

2020Aging125 citationsDOIOpen Access PDF

Abstract

A modification on MALAT1.

Topics & Concepts

Cancer researchEpithelial–mesenchymal transitionFibrosisMALAT1Extracellular matrixTransforming growth factorMedicineKidney diseaseBiologyInternal medicineMetastasisLong non-coding RNACell biologyDownregulation and upregulationCancerBiochemistryGeneCancer-related molecular mechanisms researchRNA modifications and cancerCancer-related gene regulation