IL-1ra treatment prevents chronic social defeat stress-induced depression-like behaviors and glutamatergic dysfunction via the upregulation of CREB-BDNF
Mingxing Li, Li Han, Junli Xiao, Song Zhang, Guangya Liu, Xuejiao Sun
Topics & Concepts
Social defeatCREBGlutamatergicHippocampusInterleukin 1 receptor antagonistPsychologyChronic stressNeuroscienceReceptor antagonistEndocrinologyAntagonistInternal medicineGlutamate receptorMedicineReceptorChemistryGeneTranscription factorBiochemistryTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms