Design, synthesis, and in vitro and in vivo biological evaluation of dihydroartemisinin derivatives as potent anti-cancer agents with ferroptosis-inducing and apoptosis-activating properties
Qian Xu, Hao Deng, Xing Huang, Guoqing Chen, Yuan Quan, Yalan Wang, Jinying Liu, Rui Yan, Wen-Zhe Nie, Qing‐Kun Shen, Zhe‐Shan Quan, Hong-Yan Guo, Hong-Yan Guo
Topics & Concepts
DihydroartemisininChemistryIn vivoIn vitroApoptosisBiological activityCancer cellStereochemistryPharmacologyCancerCombinatorial chemistryBiochemistryArtemisininImmunologyPlasmodium falciparumInternal medicineBiotechnologyBiologyMedicineMalariaCancer Mechanisms and TherapyFerrocene Chemistry and ApplicationsPeptidase Inhibition and Analysis