Pharmacological blockade of HDAC3 accelerates diabetic wound healing by regulating macrophage activation
Kalyani Karnam, Kavitha Sedmaki, Pravesh Sharma, Ashutosh Mahale, Balaram Ghosh, Onkar Prakash Kulkarni
Topics & Concepts
HDAC3Wound healingAngiogenesisStreptozotocinMacrophage polarizationIntegrin alpha MOxidative stressM2 MacrophageDownregulation and upregulationInflammationNeovascularizationChemistryMacrophageImmunologyPharmacologyMedicineCancer researchImmune systemHistone deacetylaseEndocrinologyDiabetes mellitusHistoneBiochemistryIn vitroGeneHistone Deacetylase Inhibitors ResearchImmune cells in cancerWound Healing and Treatments