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Phytochemical analysis, antioxidant, anticancer, and antibacterial potential of Alpinia galanga (L.) rhizome

Ibrahim M. Aziz, Akram A. Alfuraydi, Omer M. Almarfadi, Mourad A. M. Aboul‐Soud, Abdullah K. Alshememry, Asma N. Alsaleh, Fahad N. Almajhdi

2024Heliyon13 citationsDOIOpen Access PDF

Abstract

of 125.35 ± 4.28 and 182.49 ± 3.19 μg/ml, respectively. AgRE exhibited considerable antimicrobial activity against all bacterial strains, with MIC values ranging from 7.81 ± 1.53 to 62.5 ± 3.28 μg/ml. The MD results revealed that ethyl-4-(2-methylpropyl)-benzene had the greatest binding energy with NADPH oxidase, with a Glide score of -6848 kcal/mol, followed by 2-methoxy-phenol (-5111 kcal/mol). Taken together, we report the interesting antioxidant, antibacterial, and anticancer properties of AgRE, which warrant further investigation. AgRE is a promising natural resource that could be used to combat complicated diseases such as cancer and bacterial infections.

Topics & Concepts

PhytochemicalRhizomeTraditional medicineAntioxidantZingiberaceaeChemistryBiologyMedicineBiochemistryGinger and Zingiberaceae researchPhytochemistry and Biological ActivitiesNatural Antidiabetic Agents Studies
Phytochemical analysis, antioxidant, anticancer, and antibacterial potential of Alpinia galanga (L.) rhizome | Litcius