METTL3 Inhibition Suppresses Cell Growth and Survival in Colorectal Cancer via ASNS Downregulation
Yang Yu, Yanan Hai, Hongfeng Zhou, Wenfang Bao, Xiaowei Hu, Yong Gao, Jin Wu
Abstract
Our findings suggest that STM2457 may serve as a potential therapeutic agent and ASNS may be a new promising therapeutic target for CRC.
Topics & Concepts
Downregulation and upregulationColorectal cancerCancer researchCancerMechanism (biology)MedicineIncidence (geometry)Cell growthMethyltransferaseOncologyInternal medicineChemistryBiochemistryGeneMethylationEpistemologyPhilosophyOpticsPhysicsRNA modifications and cancerHVDC Systems and Fault ProtectionCancer-related gene regulation