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Parameter estimation of the structured illumination pattern based on principal component analysis (PCA): PCA-SIM

Xin Chen, Yiwei Hou, Peng Xi

2023Light Science & Applications16 citationsDOIOpen Access PDF

Abstract

Principal component analysis (PCA), a common dimensionality reduction method, is introduced into SIM to identify the frequency vectors and pattern phases of the illumination pattern with precise subpixel accuracy, fast speed, and noise-robustness, which is promising for real-time and long-term live-cell imaging.

Topics & Concepts

Principal component analysisSubpixel renderingPattern recognition (psychology)Dimensionality reductionArtificial intelligenceRobustness (evolution)Curse of dimensionalitySparse PCAComputer scienceMathematicsPixelBiochemistryGeneChemistryAdvanced Fluorescence Microscopy TechniquesCell Image Analysis TechniquesImage Processing Techniques and Applications
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