The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
Étienne Humblin, Isabel Korpas, Nataliya Prokhnevska, Abishek Vaidya, Dan Filipescu, Jiahua Lu, Verena van der Heide, Carlos Alberto de Carvalho Fraga, Tesia Bobrowski, Adam Marks, Matthew D. Park, Helder I. Nakaya, Emily Bernstein, Brian D. Brown, Amaia Lujambio, David Dominguez-Sola, Brad R. Rosenberg, Alice O. Kamphorst
Topics & Concepts
BiologyFunction (biology)CD8Cytotoxic T cellCell biologyImmune systemComputational biologyImmunologyBiochemistryIn vitroImmune Cell Function and InteractionT-cell and B-cell ImmunologyNeuroinflammation and Neurodegeneration Mechanisms