Fluorescent probes for targeting the Golgi apparatus: design strategies and applications
Silin Xu, Kai‐Cheng Yan, Zhi-Hong Xu, Yuan Wang, Tony D. James
Abstract
lysosomes and mitochondria), Golgi-targeting strategies are still in their infancy, therefore it is important to develop more Golgi-targeting probes. This review systematically summarizes the currently reported Golgi-specific fluorescent probes, and highlights the design strategies, mechanisms, and biological uses of these probes, we have structured the review based on the different targeting groups. In addition, we highlight the future challenges and opportunities in the development of Golgi-specific imaging agents and therapeutic systems.
Topics & Concepts
Golgi apparatusFluorescenceIn situNanotechnologyComputer scienceChemistryBiophysicsMaterials scienceBiologyBiochemistryCellPhysicsOpticsOrganic chemistryMolecular Sensors and Ion DetectionReceptor Mechanisms and SignalingLipid Membrane Structure and Behavior