Continuous evolution of SpCas9 variants compatible with non-G PAMs
Shannon M. Miller, Tina Wang, Peyton B. Randolph, Mandana Arbab, Max W. Shen, Tony P. Huang, Żaneta Matuszek, Gregory A. Newby, Holly A. Rees, David R. Liu
Topics & Concepts
Cas9BiologyCRISPRComputational biologyGenome editingDirected evolutionSubgenomic mRNAGeneticsGeneMutantCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniques