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Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

McLane J. Watson, Paolo Vignali, Steven J. Mullett, Abigail E. Overacre-Delgoffe, Ronal M. Peralta, Stephanie Grebinoski, Ashley V. Menk, Natalie Rittenhouse, Kristin DePeaux, Ryan D. Whetstone, Dario A.A. Vignali, Timothy W. Hand, Amanda C. Poholek, Brett M. Morrison, Jeffrey D. Rothstein, Stacy G. Wendell, Greg M. Delgoffe

2021Nature1,246 citationsDOIOpen Access PDF

Topics & Concepts

EffectorImmune systemGlycolysisTumor microenvironmentCell biologyImmunotherapyBiologyCancer researchGlucose uptakeHomeostasisMetabolismChemistryBiochemistryImmunologyEndocrinologyInsulinImmune Cell Function and InteractionCancer, Hypoxia, and MetabolismImmune cells in cancer
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid | Litcius