Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development
Anna S. Fedl, Hiromi Tagoh, Sarah Gruenbacher, Qiong Sun, Robyn L. Schenk, Kimon Froussios, Markus Jaritz, Meinrad Busslinger, Tanja A. Schwickert
Topics & Concepts
Transcription factorPAX5B cellIRF4BiologyChromatinLymphopoiesisRepressorIRF8Cell biologyRAG2Recombination-activating geneGeneMolecular biologyGeneticsHaematopoiesisAntibodyStem cellRecombinationImmune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy research