Structural elucidation and anti-nonalcoholic fatty liver disease activity of <i>Polygonatum cyrtonema</i> Hua polysaccharide
Wei Liu, Taili Shao, Lei Tian, Zhengrui Ren, Lan Gao, Zhiyan Tang, Zheng Fang, Pingchuan Yuan, Chunyan Liu, Jikun Li, Guodong Wang, Jun Han
Abstract
experiments showed that PCP1 mitigates liver pathological damage, improves abnormal lipid metabolism and oxidative stress, promotes the production of short-chain fatty acids, and balances the composition of the intestinal microbiota in non-alcoholic fatty liver disease (NAFLD) mice. Thus, PCP1 can be used as a natural ingredient in functional foods for the treatment of NAFLD.
Topics & Concepts
PolysaccharideNonalcoholic fatty liver diseaseChemistryMonosaccharideBiochemistryFructoseRhizomeMannoseChemical structureFatty acidFatty liverTraditional medicineMedicineDiseaseInternal medicineOrganic chemistryLiver Disease Diagnosis and TreatmentLipid metabolism and disordersDiet, Metabolism, and Disease