Visible-light-mediated synthesis of oxime esters <i>via</i> multicomponent reactions of aldehydes, aryl amines, and <i>N</i>-hydroxyphthalimide esters

Abstract

-hydroxyphthalimide (NHPI) esters were used as substrates in this three-component reaction, and eosin Y was used as a crucial photocatalyst for the reaction. Wide ranges of aldehydes and NHPI esters were well tolerated in this reaction method, generating various oxime esters with high efficiency under mild reaction conditions. This visible-light-mediated methodology will be a promising approach to synthesize useful oxime esters in a single step.

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