Litcius/Paper detail

Potential intervariant and intravariant recombination of Delta and Omicron variants

Lulan Wang, Hangyu Zhou, Jiaying Li, Ye‐Xiao Cheng, Shilei Zhang, Saba R. Aliyari, Aiping Wu, Genhong Cheng

2022Journal of Medical Virology27 citationsDOIOpen Access PDF

Abstract

Among numerous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concerns, Omicron is more infectious and immune-escaping, while Delta is more pathogenic. Here, we provide evidence for both intervariant and intravariant recombination of the rapidly evolving new SARS-CoV-2 genomes, including XD/XE/XF and BA.3, raising concerns of potential more infectious, immune-escaping, and disease-causing Omicron and Delta-Omicron variants.

Topics & Concepts

RecombinationVirologyImmune systemGenomeBiologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)GeneticsInfectious disease (medical specialty)GeneDiseaseMedicinePathologySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesViral gastroenteritis research and epidemiology