Umpolung Difunctionalization of Carbonyls via Visible-Light Photoredox Catalytic Radical-Carbanion Relay
Shun Wang, Bei‐Yi Cheng, Matea Sršen, Burkhard König
Abstract
carbanions. More than 80 substrate examples demonstrate the broad applicability of this reaction sequence. A series of investigations including radical inhibition, deuterium labeling, fluorescence quenching, cyclic voltammetry, and control experiments support the proposed radical-carbanion relay mechanism.
Topics & Concepts
CarbanionChemistryRadicalPhotochemistryPhotoredox catalysisUmpolungQuenching (fluorescence)NucleophileElectrophileCombinatorial chemistryCatalysisOrganic chemistryFluorescencePhotocatalysisQuantum mechanicsPhysicsFluorine in Organic ChemistrySulfur-Based Synthesis TechniquesRadical Photochemical Reactions