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Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury

Carolyn Tallon, Silvia Picciolini, Seung‐Wan Yoo, Ajit G. Thomas, Arindom Pal, Jesse Alt, Cristiano Carlomagno, Alice Gualerzi, Rana Rais, Norman J. Haughey, Marzia Bedoni, Barbara S. Slusher

2021Biochemical Pharmacology42 citationsDOIOpen Access PDF

Topics & Concepts

MicrogliaPharmacologyIn vivoExtracellular vesicleExtracellularIntegrin alpha MChemistryMedicineInflammationImmunologyBiologyBiochemistryImmune systemMicrovesiclesGenemicroRNABiotechnologyExtracellular vesicles in diseaseNeuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders
Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury | Litcius