Microneedle arrays integrated with microfluidic systems: Emerging applications and fluid flow modeling
Abdollah Ahmadpour, Pelin Kübra İşgör, Berk Ural, Busra Nimet Eren, Misagh Rezapour Sarabi, Metin Muradoğlu, Savaş Taşoğlu
Abstract
Microneedle arrays are patches of needles at micro- and nano-scale, which are competent and versatile technologies that have been merged with microfluidic systems to construct more capable devices for biomedical applications, such as drug delivery, wound healing, biosensing, and sampling body fluids. In this paper, several designs and applications are reviewed. In addition, modeling approaches used in microneedle designs for fluid flow and mass transfer are discussed, and the challenges are highlighted.
Topics & Concepts
MicrofluidicsNanotechnologyComputer scienceFluid dynamicsMaterials sciencePhysicsMechanicsAdvancements in Transdermal Drug DeliveryMicrofluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing Technologies