DegP Initiates Regulated Processing of Filamentous Hemagglutinin in Bordetella bronchiseptica
Richard Johnson, Zachary M. Nash, Margaret R. Dedloff, John C. Shook, Peggy A. Cotter
Abstract
species to prevent clearance by phagocytic cells, which is critical for bacterial persistence in the lower respiratory tract. Our findings also highlight an underappreciated role for HtrA family proteases in processing specific bacterial virulence factors.
Topics & Concepts
Periplasmic spaceProteasesMicrobiologyFilamentous haemagglutinin adhesinVirulenceProteaseBordetella bronchisepticaBordetella pertussisGroELBiologyBordetellaVirulence factorFimbriaSecretionPertactinBacteriaCell biologyBiochemistryEscherichia coliGenePertussis toxinEnzymeSignal transductionGeneticsG proteinBacterial Infections and VaccinesEscherichia coli research studiesRNA and protein synthesis mechanisms