Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13
Sun Kyung Kim, Miles Sasha Dickinson, Janet Finer-Moore, Ziqiang Guan, Robyn M. Kaake, Ignacia Echeverria, Jen Chen, Ernst H. Pulido, Andrej Šali, Nevan J. Krogan, Oren S. Rosenberg, Robert M. Stroud
Topics & Concepts
Acyl carrier proteinPolyketide synthasePolyketideMycolic acidLinkerAntimycobacterialBiochemistryTransferaseEnzymeStereochemistryChemistryFatty acid synthaseMycobacterium tuberculosisElectrospray ionizationMycobacteriumBiologyBacteriaBiosynthesisMass spectrometryOperating systemGeneticsTuberculosisMedicinePathologyChromatographyComputer scienceBiochemical and Molecular ResearchMicrobial Natural Products and BiosynthesisEnzyme Structure and Function