<i>Mycobacterium tuberculosis</i>borderline<i>rpoB</i>mutations: emerging from the unknown
Armand Van Deun, Tom Decroo, K. J. M. Aung, M. Anwar Hossain, Mourad Gumusboga, Willem Bram de Rijk, Sabira Tahseen, Bouke C. de Jong, Leen Rigouts
Abstract
<b>Despite their name, borderline <i>rpoB</i> mutations are correlated with unfavourable outcomes when rifampicin-throughout treatment is used. They may become the drivers of rifampicin-resistant tuberculosis. Second-line treatment is recommended.</b> https://bit.ly/3nbkZjt
Topics & Concepts
rpoBMedicineRifampicinMycobacterium tuberculosisTuberculosisMutationInternal medicineMicrobiologyVirologyGeneticsGenePathologyBiologyTuberculosis Research and EpidemiologyMycobacterium research and diagnosisDiagnosis and treatment of tuberculosis