Emergence and Expansion of a Carbapenem-Resistant Pseudomonas aeruginosa Clone Are Associated with Plasmid-Borne <i>bla</i> <sub>KPC-2</sub> and Virulence-Related Genes
Yanyan Hu, Congcong Liu, Qi Wang, Yu Zeng, Qiaoling Sun, Linbin Shu, Jiayue Lu, Jiacang Cai, Shaolin Wang, Rong Zhang, Zuowei Wu
Abstract
Health care-associated infections, also known as nosocomial infections, are the most frequent adverse events in health care delivery worldwide, causing high rates of morbidity and mortality and high health care costs. Pseudomonas aeruginosa is one of the leading bacterial species causing health care-associated infections. Carbapenems are the most effective antimicrobial agents for the treatment of its severe infections.
Topics & Concepts
Pseudomonas aeruginosaVirulencePlasmidAntimicrobialMicrobiologyCarbapenemclone (Java method)BiologyMedicineGeneBacteriaAntibioticsGeneticsAntibiotic Resistance in BacteriaBacterial biofilms and quorum sensingVibrio bacteria research studies