β-Carboline tethered cinnamoyl 2-aminobenzamides as class I selective HDAC inhibitors: Design, synthesis, biological activities and modelling studies
Hari Krishna Namballa, Pratibha Anchi, Kesari Lakshmi Manasa, Jay Prakash Soni, Chandraiah Godugu, Nagula Shankaraiah, Ähmed Kamal
Topics & Concepts
ChemistryIC50In vitroBiochemistryDAPICell cultureCytotoxicityAnnexinCell cycleApoptosisPharmacologyBiologyGeneticsHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisProtein Degradation and Inhibitors