Current status of <i>Helicobacter pylori</i> eradication and risk factors for eradication failure
Tianlian Yan, Jianguo Gao, Jinghua Wang, Dan Chen, Chao Lü, Chengfu Xu
Abstract
BACKGROUND: ) eradication rate is decreasing in the general population of China. AIM: eradication status in real-world clinical practice and to explore factors related to eradication failure. METHODS: infection who were treated with standard 14-d quadruple therapy and received a test of cure at a provincial medical institution between June 2018 and May 2019 were enrolled. Demographic and clinical data were recorded. Eradication rates were calculated and compared between regimens and subgroups. Multivariate analysis was performed to identify predictors of eradication failure. RESULTS: = 0.001). Multivariate regression analysis found that older age, prior therapy, and use of omeprazole or pantoprazole were associated with an increased risk of eradication failure. CONCLUSION: The total eradication rate is 76.6%. Amoxicillin-containing regimens are superior to other regimens. Age, prior therapy, and use of omeprazole or pantoprazole are independent risk factors for eradication failure.