Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis
Achilleas Floudas, Nuno Neto, Carl Orr, Mary Canavan, Phil Gallagher, Conor Hurson, Michael G. Monaghan, Sunil Nagpar, Ronan Mullan, Douglas J. Veale, Ursula Fearon
Topics & Concepts
MedicineImmunologyT cellSynovial fluidRheumatoid arthritisPeripheral blood mononuclear cellArthritisCD8Flow cytometryPopulationInflammationCellPathologyImmune systemBiologyOsteoarthritisIn vitroBiochemistryGeneticsEnvironmental healthAlternative medicineRheumatoid Arthritis Research and TherapiesCancer Immunotherapy and BiomarkersSingle-cell and spatial transcriptomics