Biological behavior exploration of a paclitaxel-eluting poly-<scp>l</scp>-lactide-coated Mg–Zn–Y–Nd alloy intestinal stent <i>in vivo</i>
Zhanhui Wang, Zongbin Sun, Baowei Han, Qiuxia Zheng, Shaopeng Liu, Bingbing Zhang, Tinghe Duan
Abstract
biocompatibility demonstrated that the MAO/PLLA/paclitaxel/Mg-Zn-Y-Nd alloy stents could significantly inhibit intestinal tissue proliferation compared to the PLLA/Mg-Zn-Y-Nd alloy stents, thus providing the basis for designing excellent biodegradable drug stents.
Topics & Concepts
BiocompatibilityPaclitaxelIn vivoStentAlloyBiomedical engineeringMaterials scienceScanning electron microscopeNuclear chemistryPharmacologyChemistryMetallurgyMedicineSurgeryBiologyComposite materialChemotherapyBiotechnologyMagnesium Alloys: Properties and ApplicationsEsophageal and GI PathologyMagnesium in Health and Disease