Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants
Michael Korenkov, Matthias Zehner, Hadas Cohen‐Dvashi, Aliza Borenstein-Katz, Lisa Kottege, Hanna Janicki, Kanika Vanshylla, Timm Weber, Henning Gruell, Manuel Koch, Ron Diskin, Christoph Kreer, Florian Klein
Topics & Concepts
Somatic hypermutationNeutralizationAntibodyBiologyVirologyNeutralizing antibodyAffinity maturationBystander effectMutationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Immune escapeGeneticsCoronavirus disease 2019 (COVID-19)ImmunologyGeneB cellImmune systemMedicineInfectious disease (medical specialty)PathologyDiseaseSARS-CoV-2 and COVID-19 ResearchCAR-T cell therapy researchViral Infections and Immunology Research